Future tech
Some basic research questions cannot be asked because suitable technologies are not available, or only become apparent once a technology is invented - the known (and unknown) unknowns.
To be able to ask these questions, a major focus of the lab is the invention, development and application of future tech platforms and pipelines for biology and drug discovery.
These include:
Reactivity profiling for the discovery of antimicrobial targets.
Proteome engineering for antimicrobial drug target prioritization.
Cellular barcoding of eukaryotic pathogens for within-host population
dynamics.
Multiplexed in vivo phenotypic screens for next generation antimicrobials.